SDC2 Antibody

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ProSci
Product Code: PSI-18-291
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-291-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of HeLa cells, using SDC2 antibody (18-291) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded mouse lung using SDC2 antibody (18-291) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver damage using SDC2 antibody (18-291) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using SDC2 antibody (18-291) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of HeLa cells, using SDC2 antibody (18-291) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded mouse lung using SDC2 antibody (18-291) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver damage using SDC2 antibody (18-291) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using SDC2 antibody (18-291) at dilution of 1:100 (40x lens).

Documents

Further Information

Additional Names:
CD362, HSPG, HSPG1, SYND2, syndecan-2, cell surface-associated heparan sulfate proteoglycan 1, fibroglycan, heparan sulfate proteoglycan 1, cell surface-associated, heparan sulfate proteoglycan core protein, syndecan proteoglycan 2
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human SDC2 (NP_002989.2).
NCBI Gene ID #:
6383
NCBI Official Name:
syndecan 2
NCBI Official Symbol:
SDC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 50kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Growth Factors, Immunology, Neuroscience, Signal Transduction
Swissprot #:
P34741
User NOte:
Optimal dilutions for each application to be determined by the researcher.