CES1 Antibody

ProSci
Product Code: PSI-18-347
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-347-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using CES1 antibody (18-347) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
2 / 2
Immunohistochemistry of paraffin-embedded human liver cancer using CES1 antibody (18-347) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using CES1 antibody (18-347) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded human liver cancer using CES1 antibody (18-347) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
CES1, ACAT, CEH, CES2, HMSE, HMSE1, MGC117365, PCE-1, SES1, TGH, REH, CE-1, hCE-1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 287-566 of human CES1 (NP_001257.4).
NCBI Gene ID #:
1066
NCBI Official Name:
carboxylesterase 1
NCBI Official Symbol:
CES1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 63kDa
Purification:
Affinity purification
Research Area:
Cancer, Immunology, Signal Transduction
Swissprot #:
P23141
User NOte:
Optimal dilutions for each application to be determined by the researcher.