SMARCC2 Antibody

ProSci
Product Code: PSI-18-417
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-417-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using SMARCC2 antibody (18-417) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 60s.
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Immunohistochemistry of paraffin-embedded rat kidney using SMARCC2 antibody (18-417) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human prostate cancer using SMARCC2 antibody (18-417) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using SMARCC2 antibody (18-417) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 60s.
Immunohistochemistry of paraffin-embedded rat kidney using SMARCC2 antibody (18-417) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate cancer using SMARCC2 antibody (18-417) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
BAF17CRACC2, CSS8, Rsc8, SWI/SNF complex subunit SMARCC2, SWI/SNF complex 170 kDa subunit, SWI3-like protein, chromatin remodeling complex BAF170 subunit, mammalian chromatin remodeling complex BRG1-associated factor 170
Application Note:
WB: 1:200 - 1:2000

IHC: 1:50 - 1:200
Background:
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMARCC2 (NP_620706.1).
NCBI Gene ID #:
6601
NCBI Official Name:
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
NCBI Official Symbol:
SMARCC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 171kDa
Purification:
Affinity purification
Research Area:
Other
Swissprot #:
Q8TAQ2
User NOte:
Optimal dilutions for each application to be determined by the researcher.