ProSci

APCS Antibody

Product Code:
 
PSI-18-435
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Shipping:
 
Blue Ice or RT
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
1 / 4
Western blot analysis of extracts of 293T cells, using APCS antibody (18-435) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 50s.
2 / 4
Immunohistochemistry of paraffin-embedded rat lung using APCS antibody (18-435) at dilution of 1:100 (40x lens).
3 / 4
Immunohistochemistry of paraffin-embedded human colon using APCS antibody (18-435) at dilution of 1:100 (40x lens).
4 / 4
Immunohistochemistry of paraffin-embedded mouse brain using APCS antibody (18-435) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of 293T cells, using APCS antibody (18-435) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 50s.
Immunohistochemistry of paraffin-embedded rat lung using APCS antibody (18-435) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon using APCS antibody (18-435) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using APCS antibody (18-435) at dilution of 1:100 (40x lens).

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PSI-18-435-50uL50uL£433.00
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Further Information

Additional Names:
APCS, MGC88159, PTX2, SAP, HEL-S-92n
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-223 of human APCS (NP_001630.1).
NCBI Gene ID #:
325
NCBI Official Name:
amyloid P component, serum
NCBI Official Symbol:
APCS
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 30kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
P02743
User NOte:
Optimal dilutions for each application to be determined by the researcher.