CHIT1 Antibody
| Code | Size | Price |
|---|
| PSI-18-448-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
CHIT1, plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase, OTTHUMP00000217085, OTTHUMP00000217084, OTTHUMP00000217083, MGC125322, FLJ00314, chitotriosidase-1, chitinase-1, chitinase 1 (chitotriosidase), CHIT, CHI3, CHITD
Application Note:
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IHC: 1:50 - 1:200
Background:
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1).
NCBI Gene ID #:
1118
NCBI Official Name:
chitinase 1 (chitotriosidase)
NCBI Official Symbol:
CHIT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 52kDa
Purification:
Affinity purification
Research Area:
Immunology, Innate Immunity
Swissprot #:
Q13231
User NOte:
Optimal dilutions for each application to be determined by the researcher.