PGR Antibody

ProSci
Product Code: PSI-18-504
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-504-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse lung, using PGR antibody (18-504) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
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Immunohistochemistry of paraffin-embedded mouse brain using PGR antibody (18-504) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat brain using PGR antibody (18-504) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human lung cancer using PGR antibody (18-504) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of mouse lung, using PGR antibody (18-504) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.
Immunohistochemistry of paraffin-embedded mouse brain using PGR antibody (18-504) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using PGR antibody (18-504) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human lung cancer using PGR antibody (18-504) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
PGR, NR3C3, PR
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 830 to the C-terminus of human PGR (NP_000917.3).
NCBI Gene ID #:
5241
NCBI Official Name:
progesterone receptor
NCBI Official Symbol:
PGR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 94kDa
Purification:
Affinity purification
Research Area:
Cancer, Neuroscience, Signal Transduction, Transcription
Swissprot #:
P06401
User NOte:
Optimal dilutions for each application to be determined by the researcher.