PRKCE Antibody

Protein kinase C epsilon type, nPKC-epsilon, PRKCE, PKCE

WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

batch dependent

Unconjugated

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human PRKCE (NP_005391.1).

5581

Protein kinase C epsilon type

PRKCE

Homo sapiens

Liquid

Observed: 100kDa

Affinity purification

Apoptosis, Cell Cycle, Immunology, Signal Transduction

Q02156

Optimal dilutions for each application to be determined by the researcher.