GAD1 Antibody
| Code | Size | Price |
|---|
| PSI-18-876-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
GAD1, SCP, OTTHUMP00000204995, OTTHUMP00000204994, OTTHUMP00000204993, OTTHUMP00000204990, glutamate decarboxylase 67 kDa isoform, glutamate decarboxylase 1 (brain, 67kDa), glutamate decarboxylase 1, GAD-67, GAD, FLJ45882, 67 kDa glutamic acid decarboxylase, GAD67
Application Note:
WB: 1:500 - 1:2000
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human GAD1 (NP_000808.2).
NCBI Gene ID #:
2571
NCBI Official Name:
glutamate decarboxylase 1 (brain, 67kDa)
NCBI Official Symbol:
GAD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 67kDa
Purification:
Affinity purification
Research Area:
Immunology, Neuroscience, Signal Transduction
Swissprot #:
Q99259
User NOte:
Optimal dilutions for each application to be determined by the researcher.