KISS1R Antibody

ProSci
Product Code: PSI-18-887
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-18-887-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 4
Western blot analysis of extracts of SW480 cells, using KISS1R antibody (18-887) at 1:350 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
2 / 4
Immunohistochemistry of paraffin-embedded rat brain using KISS1R Antibody (18-887) at dilution of 1:100 (40x lens).
3 / 4
Immunohistochemistry of paraffin-embedded human B cell lymphoma using KISS1R Antibody (18-887) at dilution of 1:100 (40x lens).
4 / 4
Immunohistochemistry of paraffin-embedded mouse brain using KISS1R Antibody (18-887) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of SW480 cells, using KISS1R antibody (18-887) at 1:350 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded rat brain using KISS1R Antibody (18-887) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human B cell lymphoma using KISS1R Antibody (18-887) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using KISS1R Antibody (18-887) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
AXOR12, CPPB1, GPR54, HH8, HOT7T175, KISS-1R, kiSS-1 receptor, G protein-coupled receptor 54, G-protein coupled receptor OT7T175, hypogonadotropin-1, kisspeptins receptor, metastin receptor
Application Note:
WB: 1:500 - 1:1000

IHC: 1:50 - 1:100
Background:
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide of human KISS1R
NCBI Gene ID #:
84634
NCBI Official Name:
KISS1 receptor
NCBI Official Symbol:
KISS1R
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 43kDa
Purification:
Affinity purification
Research Area:
Neuroscience, Signal Transduction
Swissprot #:
Q969F8
User NOte:
Optimal dilutions for each application to be determined by the researcher.