LCN2 Antibody

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ProSci
Product Code: PSI-18-978
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-18-978-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse testis, using LCN2 antibody (18-978) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 20s.
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Immunofluorescence analysis of rat kidney using LCN2 antibody (18-978) at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of mouse kidney using LCN2 antibody (18-978) at dilution of 1:100. Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of mouse testis, using LCN2 antibody (18-978) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 20s.
Immunofluorescence analysis of rat kidney using LCN2 antibody (18-978) at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of mouse kidney using LCN2 antibody (18-978) at dilution of 1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Additional Names:
Siderocalin; Oncogene 24p3; Neutrophil Gelatinase-associated Lipocalin; NGAL
Application Note:
WB: 1:500 - 1:2000

IF: 1:50 - 1:200
Background:
This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LCN2 (NP_005555.2).
NCBI Gene ID #:
3934
NCBI Official Name:
lipocalin 2
NCBI Official Symbol:
LCN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 22kDa
Purification:
Affinity purification
Research Area:
Cancer, Immunology, Signal Transduction
Swissprot #:
P80188
User NOte:
Optimal dilutions for each application to be determined by the researcher.