SLC4A4 / NBC Antibody

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ProSci
Product Code: PSI-19-594
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-19-594-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of 293T cells, using SLC4A4 / NBC antibody (19-594) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded human prostate using SLC4A4 / NBC antibody (19-594) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat kidney using SLC4A4 / NBC antibody (19-594) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using SLC4A4 / NBC antibody (19-594) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of 293T cells, using SLC4A4 / NBC antibody (19-594) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
Immunohistochemistry of paraffin-embedded human prostate using SLC4A4 / NBC antibody (19-594) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using SLC4A4 / NBC antibody (19-594) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using SLC4A4 / NBC antibody (19-594) at dilution of 1:100 (40x lens).

Documents

Further Information

Additional Names:
HNBC1, KNBC, NBC1, NBC2, NBCe1-A, SLC4A5, hhNMC, kNBC1, pNBC, electrogenic sodium bicarbonate cotransporter 1, Na(+)/HCO3(-) cotransporter, sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas), solute carrier family 4 (sodium bicarbonate cotransporter), member 4, solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type, solute carrier family 4, sodium bicarbonate cotransporter, member 5
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human SLC4A4 / NBC (NP_003750.1).
NCBI Gene ID #:
8671
NCBI Official Name:
solute carrier family 4 member 4
NCBI Official Symbol:
SLC4A4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 135kDa
Purification:
Affinity purification
Research Area:
Neuroscience, Signal Transduction
Swissprot #:
Q9Y6R1
User NOte:
Optimal dilutions for each application to be determined by the researcher.