SIGMAR1 Antibody

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ProSci
Product Code: PSI-19-689
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-19-689-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using SIGMAR1 antibody (19-689) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human stomach using SIGMAR1 antibody (19-689) (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using SIGMAR1 antibody (19-689) (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using SIGMAR1 antibody (19-689) (40x lens).
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Western blot analysis of extracts of various cell lines, using SIGMAR1 antibody (19-689) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human stomach using SIGMAR1 antibody (19-689) (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using SIGMAR1 antibody (19-689) (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using SIGMAR1 antibody (19-689) (40x lens).

Documents

Further Information

Additional Names:
Sigma non-opioid intracellular receptor 1, Aging-associated gene 8 protein, SR31747-binding protein, SR-BP, Sigma 1-type opioid receptor, SIG-1R, Sigma1-receptor, Sigma1R, hSigmaR1, SIGMAR1, OPRS1, SRBP
Application Note:
WB: 1:500 - 1:2000

IHC: 1:100 - 1:200
Background:
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant protein of human SIGMAR1
NCBI Gene ID #:
10280
NCBI Official Name:
Sigma non-opioid intracellular receptor 1
NCBI Official Symbol:
SIGMAR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 25kDa
Purification:
Affinity purification
Research Area:
Cancer, Neuroscience, Signal Transduction
Swissprot #:
Q99720
User NOte:
Optimal dilutions for each application to be determined by the researcher.