SERPIND1 Antibody

ProSci
Product Code: PSI-19-896
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-19-896-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using SERPIND1 antibody (19-896) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Western blot analysis of extracts of various cell lines, using SERPIND1 antibody (19-896) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.

Further Information

Additional Names:
D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH1heparin cofactor 2, leuserpin 2, protease inhibitor leuserpin-2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1, serpin D1, serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Application Note:
WB: 1:500 - 1:2000
Background:
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-290 of human SERPIND1 (NP_000176.2).
NCBI Gene ID #:
3053
NCBI Official Name:
serpin family D member 1
NCBI Official Symbol:
SERPIND1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 57-69kDa
Purification:
Affinity purification
Research Area:
Other
Swissprot #:
P05546
User NOte:
Optimal dilutions for each application to be determined by the researcher.