CLEC12A Antibody

ProSci
Product Code: PSI-22-083
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-083-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of K-562 cells, using CLEC12A antibody (22-083) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 15s.

Western blot analysis of extracts of K-562 cells, using CLEC12A antibody (22-083) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 15s.

Further Information

Additional Names:
CLEC12A, C-type lectin domain family 12, member A, CLL-1, CLL1, DCAL-2, MICL, C-type lectin domain family 12 member A, C-type lectin protein CLL-1, C-type lectin superfamily, C-type lectin-like molecule-1, dendritic cell-associated lectin 2, myeloid inhib
Application Note:
WB: 1:500 - 1:2000
Background:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 66-265 of human CLEC12A (NP_612210.4).
NCBI Gene ID #:
160364
NCBI Official Name:
C-type lectin domain family 12, member A
NCBI Official Symbol:
CLEC12A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 24kDa
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
Q5QGZ9
User NOte:
Optimal dilutions for each application to be determined by the researcher.