M6PR Antibody

ProSci
Product Code: PSI-22-107
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-107-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse kidney, using M6PR antibody (22-107) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 40s.
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Immunohistochemistry of paraffin-embedded human liver damage using M6PR antibody (22-107) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human stomach using M6PR antibody (22-107) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using M6PR antibody (22-107) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of mouse kidney, using M6PR antibody (22-107) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 40s.
Immunohistochemistry of paraffin-embedded human liver damage using M6PR antibody (22-107) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using M6PR antibody (22-107) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using M6PR antibody (22-107) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
M6PR, CD-MPR, FLJ32994, MPR46, SMPR, MPR 46, MPR-46
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-185 of human M6PR (NP_002346.1).
NCBI Gene ID #:
4074
NCBI Official Name:
mannose-6-phosphate receptor (cation dependent)
NCBI Official Symbol:
M6PR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 31kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Growth Factors, Immunology, Innate Immunity, Signal Transduction
Swissprot #:
P20645
User NOte:
Optimal dilutions for each application to be determined by the researcher.