CCBL1 Antibody

ProSci
Product Code: PSI-22-298
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-298-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using CCBL1 Antibody (22-298) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded mouse liver using CCBL1 antibody (22-298) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using CCBL1 antibody (22-298) at dilution of 1:100 (40x lens).
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Immunofluorescence analysis of U2OS cells using CCBL1 antibody (22-298). Blue: DAPI for nuclear staining.

Western blot analysis of extracts of various cell lines, using CCBL1 Antibody (22-298) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded mouse liver using CCBL1 antibody (22-298) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using CCBL1 antibody (22-298) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using CCBL1 antibody (22-298). Blue: DAPI for nuclear staining.

Further Information

Additional Names:
CCBL1, cysteine conjugate-beta lyase, glutamine transaminase K, kyneurenine aminotransferase, GTK, KATI, MGC29624, cytoplasmic cysteine conjugate-beta lyase, glutamine-phenylpyruvate aminotransferase, kynurenine aminotransferase I, KAT1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200

IF: 1:10 - 1:100
Background:
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCBL1 (NP_001116144.1).
NCBI Gene ID #:
883
NCBI Official Name:
cysteine conjugate-beta lyase, cytoplasmic
NCBI Official Symbol:
CCBL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 48kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
Q16773
User NOte:
Optimal dilutions for each application to be determined by the researcher.