GDAP1 Antibody

ProSci
Product Code: PSI-22-343
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-343-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 4
Western blot analysis of extracts of various cell lines, using GDAP1 antibody (22-343) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
2 / 4
Immunohistochemistry of paraffin-embedded rat kidney using GDAP1 antibody (22-343) at dilution of 1:100 (40x lens).
3 / 4
Immunohistochemistry of paraffin-embedded rat heart using GDAP1 antibody (22-343) at dilution of 1:100 (40x lens).
4 / 4
Immunohistochemistry of paraffin-embedded mouse kidney using GDAP1 antibody (22-343) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using GDAP1 antibody (22-343) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded rat kidney using GDAP1 antibody (22-343) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat heart using GDAP1 antibody (22-343) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using GDAP1 antibody (22-343) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
CMT4, CMT4A, CMTRIA, ganglioside-induced differentiation-associated protein 1, Charcot-Marie-Tooth neuropathy 4A
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human GDAP1 (NP_001035808.1).
NCBI Gene ID #:
54332
NCBI Official Name:
ganglioside induced differentiation associated protein 1
NCBI Official Symbol:
GDAP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 38kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q8TB36
User NOte:
Optimal dilutions for each application to be determined by the researcher.