RAPSN Antibody

ProSci
Product Code: PSI-22-432
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-432-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using RAPSN Antibody (22-432) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 15s.
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Immunohistochemistry of paraffin-embedded human stomach using RAPSN antibody (22-432) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded rat brain using RAPSN antibody (22-432) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using RAPSN Antibody (22-432) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 15s.
Immunohistochemistry of paraffin-embedded human stomach using RAPSN antibody (22-432) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using RAPSN antibody (22-432) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
RAPSN, CMS1D, CMS1E, MGC3597, RAPSYN, RNF205
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human RAPSN (NP_116034.2).
NCBI Gene ID #:
5913
NCBI Official Name:
receptor-associated protein of the synapse
NCBI Official Symbol:
RAPSN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 43kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q13702
User NOte:
Optimal dilutions for each application to be determined by the researcher.