SETMAR Antibody
| Code | Size | Price |
|---|
| PSI-22-450-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
SETMAR, SET domain and mariner transposase fusion gene, Mar1, HsMar1, METNASE
Application Note:
WB: 1:500 - 1:2000
IF: 1:20 - 1:50
IF: 1:20 - 1:50
Background:
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human SETMAR (NP_006506.3).
NCBI Gene ID #:
6419
NCBI Official Name:
SET domain and mariner transposase fusion gene
NCBI Official Symbol:
SETMAR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Other
Swissprot #:
Q53H47
User NOte:
Optimal dilutions for each application to be determined by the researcher.