STC1 Antibody

ProSci
Product Code: PSI-22-463
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-463-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse lung, using STC1 Antibody (22-463) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded rat kidney using STC1 antibody (22-463) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human liver using STC1 antibody (22-463) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse heart using STC1 antibody (22-463) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of mouse lung, using STC1 Antibody (22-463) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded rat kidney using STC1 antibody (22-463) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human liver using STC1 antibody (22-463) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse heart using STC1 antibody (22-463) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
STC1, STC
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-247 of human STC1 (NP_003146.1).
NCBI Gene ID #:
6781
NCBI Official Name:
stanniocalcin 1
NCBI Official Symbol:
STC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 28kDa
Purification:
Affinity purification
Research Area:
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Swissprot #:
P52823
User NOte:
Optimal dilutions for each application to be determined by the researcher.