TSHB Antibody

ProSci
Product Code: PSI-22-480
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-480-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded human prostate using TSHB antibody (22-480) at dilution of 1:100 (40x lens).
2 / 3
Immunohistochemistry of paraffin-embedded mouse lung using TSHB antibody (22-480) at dilution of 1:100 (40x lens).
3 / 3
Immunofluorescence analysis of U2OS cells using TSHB antibody (22-480). Blue: DAPI for nuclear staining.

Immunohistochemistry of paraffin-embedded human prostate using TSHB antibody (22-480) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using TSHB antibody (22-480) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using TSHB antibody (22-480). Blue: DAPI for nuclear staining.

Further Information

Additional Names:
Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH-B, TSH-beta, Thyrotropin beta chain, Thyrotropin alfa, TSHB
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100

IF: 1:50 - 1:100
Background:
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-138 of human TSHB (NP_000540.2).
NCBI Gene ID #:
7252
NCBI Official Name:
Thyrotropin subunit beta
NCBI Official Symbol:
TSHB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cancer, Cell Cycle, Growth Factors, Neuroscience, Signal Transduction
Swissprot #:
P01222
User NOte:
Optimal dilutions for each application to be determined by the researcher.