FANCL Antibody

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ProSci
Product Code: PSI-22-497
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-497-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of mouse thymus, using FANCL antibody (22-497) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded mouse stomach using FANCL antibody (22-497) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human esophagus using FANCL antibody (22-497) at dilution of 1:100 (40x lens).
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Western blot analysis of extracts of mouse thymus, using FANCL antibody (22-497) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded mouse stomach using FANCL antibody (22-497) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using FANCL antibody (22-497) at dilution of 1:100 (40x lens).

Documents

Further Information

Additional Names:
FANCL, POG, PHF9, PHD finger protein 9, FLJ10335, Fanconi anemia, complementation group L, FAAP43
Application Note:
WB: 1:200 - 1:2000

IHC: 1:20 - 1:200
Background:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human FANCL (NP_060532.2).
NCBI Gene ID #:
55120
NCBI Official Name:
Fanconi anemia, complementation group L
NCBI Official Symbol:
FANCL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 38kDa
Purification:
Affinity purification
Research Area:
Cell Cycle
Swissprot #:
Q9NW38
User NOte:
Optimal dilutions for each application to be determined by the researcher.