RAD1 Antibody

ProSci
Product Code: PSI-22-505
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-505-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded rat brain using RAD1 antibody (22-505) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse brain using RAD1 antibody (22-505) at dilution of 1:200 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse spleen using RAD1 antibody (22-505) at dilution of 1:200 (40x lens).
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Immunofluorescence analysis of MCF-7 cells using RAD1 antibody (22-505). Blue: DAPI for nuclear staining.

Immunohistochemistry of paraffin-embedded rat brain using RAD1 antibody (22-505) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse brain using RAD1 antibody (22-505) at dilution of 1:200 (40x lens).
Immunohistochemistry of paraffin-embedded mouse spleen using RAD1 antibody (22-505) at dilution of 1:200 (40x lens).
Immunofluorescence analysis of MCF-7 cells using RAD1 antibody (22-505). Blue: DAPI for nuclear staining.

Further Information

Additional Names:
RAD1, DNA repair exonuclease REC1, RAD1 (S. pombe) homolog, REC1, RAD1 homolog (S. pombe), Exonuclease homolog RAD1, HRAD1
Application Note:
IHC: 1:20 - 1:200

IF: 1:50 - 1:200
Background:
This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human RAD1 (NP_002844.1).
NCBI Gene ID #:
5810
NCBI Official Name:
RAD1 homolog (S. pombe)
NCBI Official Symbol:
RAD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Other
Swissprot #:
O60671
User NOte:
Optimal dilutions for each application to be determined by the researcher.