NSL1 Antibody

ProSci
Product Code: PSI-22-688
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-688-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of A549 cells using NSL1 antibody (22-688).

Immunofluorescence analysis of A549 cells using NSL1 antibody (22-688).

Further Information

Additional Names:
C1orf48, DC8, MIS14, kinetochore-associated protein NSL1 homolog, NSL1, MIND kinetochore complex component, homolog, NSL1, MIS12 kinetochore complex component
Application Note:
WB: 1:500 - 1:2000

IF: 1:50 - 1:100
Background:
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human NSL1 (NP_056286.3).
NCBI Gene ID #:
25936
NCBI Official Name:
NSL1 component of MIS12 kinetochore complex
NCBI Official Symbol:
NSL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Purification:
Affinity purification
Research Area:
Cell Cycle
Swissprot #:
Q96IY1
User NOte:
Optimal dilutions for each application to be determined by the researcher.