ADCK3 Antibody

ProSci
Product Code: PSI-22-901
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-22-901-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using ADCK3 antibody (22-901) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
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Immunohistochemistry of paraffin-embedded rat liver using ADCK3 antibody (22-901) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded human kidney using ADCK3 antibody (22-901) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse kidney using ADCK3 antibody (22-901) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of various cell lines, using ADCK3 antibody (22-901) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 30s.
Immunohistochemistry of paraffin-embedded rat liver using ADCK3 antibody (22-901) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human kidney using ADCK3 antibody (22-901) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse kidney using ADCK3 antibody (22-901) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, 2711-, aarF domain-containing protein kinase 3, ADCK3, CABC1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ADCK3 (NP_064632.2).
NCBI Gene ID #:
56997
NCBI Official Name:
Chaperone activity of bc1 complex-like, mitochondrial
NCBI Official Symbol:
ADCK3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 55kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
Q8NI60
User NOte:
Optimal dilutions for each application to be determined by the researcher.