LDB3 Antibody

LDB3, CYPHER, KIAA01613, KIAA0613, ORACLE, PDLIM6, ZASP, MFM4, CMD1C, LVNC3, LDB3Z1, LDB3Z4

WB: 1:500 - 1:2000

IF: 1:50 - 1:200

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

batch dependent

Unconjugated

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of human LDB3 (NP_001073585.1).

11155

LIM domain binding 3

LDB3

Homo sapiens

Liquid

Observed: 50kDa/90kDa

Affinity purification

Signal Transduction

O75112

Optimal dilutions for each application to be determined by the researcher.