CYB5R3 Antibody
| Code | Size | Price |
|---|
| PSI-23-012-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
OTTHUMP00000198665, OTTHUMP00000198574, NADH-cytochrome b5 reductase 3 soluble form, NADH-cytochrome b5 reductase 3 membrane-bound form, NADH-cytochrome b5 reductase 3, DIA1, B5R, cytochrome b5 reductase 3, CYB5R3
Application Note:
WB: 1:500 - 1:2000
Background:
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 125-334 of human CYB5R3 (NP_001165131.1).
NCBI Gene ID #:
1727
NCBI Official Name:
cytochrome b5 reductase 3
NCBI Official Symbol:
CYB5R3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 34-36kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
P00387
User NOte:
Optimal dilutions for each application to be determined by the researcher.