NYX Antibody

ProSci
Product Code: PSI-23-212
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-212-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of 293T cells, using NYX antibody (23-212) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
2 / 3
Immunohistochemistry of paraffin-embedded human prostate using NYX antibody (23-212) at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded mouse lung using NYX antibody (23-212) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of 293T cells, using NYX antibody (23-212) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human prostate using NYX antibody (23-212) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded mouse lung using NYX antibody (23-212) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
Nyctalopin, NYX, CLRP
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1).
NCBI Gene ID #:
60506
NCBI Official Name:
Nyctalopin
NCBI Official Symbol:
NYX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 52kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q9GZU5
User NOte:
Optimal dilutions for each application to be determined by the researcher.