AMPD1 Antibody

ProSci
Product Code: PSI-23-246
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-246-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using AMPD1 antibody (23-246) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
2 / 3
Immunohistochemistry of paraffin-embedded human esophagus using AMPD1 antibody (23-246) (40x lens).
3 / 3
Immunohistochemistry of paraffin-embedded rat brain using AMPD1 antibody (23-246) (40x lens).

Western blot analysis of extracts of various cell lines, using AMPD1 antibody (23-246) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human esophagus using AMPD1 antibody (23-246) (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using AMPD1 antibody (23-246) (40x lens).

Further Information

Additional Names:
AMPD1, adenosine monophosphate deaminase 1 (isoform M), MAD, MADA, Adenosine monophosphate deaminase-1 (muscle), OTTHUMP00000059283, MMDD
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide of human AMPD1
NCBI Gene ID #:
270
NCBI Official Name:
adenosine monophosphate deaminase 1
NCBI Official Symbol:
AMPD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 80kDa
Purification:
Affinity purification
Research Area:
Cancer, Signal Transduction
Swissprot #:
P23109
User NOte:
Optimal dilutions for each application to be determined by the researcher.