SPR Antibody

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ProSci
Product Code: PSI-23-285
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-23-285-50uL50uL£433.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using SPR antibody (23-285) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
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Immunohistochemistry of paraffin-embedded human esophagus using SPR antibody (23-285) (40x lens).
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Immunohistochemistry of paraffin-embedded rat brain using SPR antibody (23-285) (40x lens).
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Immunohistochemistry of paraffin-embedded human lung using SPR antibody (23-285) (40x lens).
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Western blot analysis of extracts of various cell lines, using SPR antibody (23-285) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human esophagus using SPR antibody (23-285) (40x lens).
Immunohistochemistry of paraffin-embedded rat brain using SPR antibody (23-285) (40x lens).
Immunohistochemistry of paraffin-embedded human lung using SPR antibody (23-285) (40x lens).

Documents

Further Information

Additional Names:
Sepiapterin reductase, SPR, SPR
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide of human SPR
NCBI Gene ID #:
6697
NCBI Official Name:
Sepiapterin reductase
NCBI Official Symbol:
SPR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 28kDa
Purification:
Affinity purification
Research Area:
Cancer, Neuroscience, Signal Transduction
Swissprot #:
P35270
User NOte:
Optimal dilutions for each application to be determined by the researcher.