AURKC Antibody

ProSci
Product Code: PSI-23-286
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-286-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 3
Immunohistochemistry of paraffin-embedded rat brain using AURKC antibody (23-286) (40x lens).
2 / 3
Immunohistochemistry of paraffin-embedded rat kidney using AURKC antibody (23-286) (40x lens).
3 / 3
Western blot analysis of extracts of various cell lines, using AURKC antibody (23-286) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.

Immunohistochemistry of paraffin-embedded rat brain using AURKC antibody (23-286) (40x lens).
Immunohistochemistry of paraffin-embedded rat kidney using AURKC antibody (23-286) (40x lens).
Western blot analysis of extracts of various cell lines, using AURKC antibody (23-286) at 1:500 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Enhanced Kit.<br/>Exposure time: 90s.

Further Information

Additional Names:
AURKC, STK13, serine/threonine kinase 13 (aurora/IPL1-like), aurora-C, aurora/IPL1-related kinase 3, aurora/IPL1/EG2 protein 2, aurora kinase C, AurC, ARK3, AIK3, AIE2, AIRK3
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100
Background:
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide of human AURKC
NCBI Gene ID #:
6795
NCBI Official Name:
aurora kinase C
NCBI Official Symbol:
AURKC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 36kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Signal Transduction
Swissprot #:
Q9UQB9
User NOte:
Optimal dilutions for each application to be determined by the researcher.