NPR3 Antibody

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ProSci
Product Code: PSI-23-425
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-425-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines, using NPR3 antibody (23-425) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 3s.
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Western blot analysis of extracts of various cell lines, using NPR3 antibody (23-425) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 3s.

Documents

Further Information

Additional Names:
NPR3, OTTHUMP00000220980, OTTHUMP00000197048, NPR-C, NPRC, natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), GUCY2B, atrial natriuretic peptide receptor type C, atrial natriuretic peptide receptor 3, atrial natriuretic peptide clearance receptor, ANPR-C, ANPRC, ANP-C, C5orf23
Application Note:
WB: 1:1000 - 1:2000

IF: 1:50 - 1:200
Background:
This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 272-541 of human NPR3 (NP_001191304.1).
NCBI Gene ID #:
4883
NCBI Official Name:
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
NCBI Official Symbol:
NPR3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 60kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Signal Transduction
Swissprot #:
P17342
User NOte:
Optimal dilutions for each application to be determined by the researcher.