TMC1 Antibody

ProSci
Product Code: PSI-23-681
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-681-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 4
Western blot analysis of extracts of mouse eye, using TMC1 antibody (23-681) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 90s.
2 / 4
3 / 4
Immunohistochemistry of paraffin-embedded human prostate using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).
4 / 4
Immunohistochemistry of paraffin-embedded human esophagus using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).

Western blot analysis of extracts of mouse eye, using TMC1 antibody (23-681) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit._Exposure time: 90s.
Immunohistochemistry of paraffin-embedded human prostate using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human esophagus using TMC1 antibody (23-681) at dilution of 1:100 (40x lens).

Further Information

Additional Names:
DFNA36, DFNB11, DFNB7, transmembrane channel-like protein 1, transmembrane cochlear-expressed protein 1, transmembrane, cochlear expressed, 1
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells. Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 600-700 of human TMC1 (NP_619636.2).
NCBI Gene ID #:
117531
NCBI Official Name:
transmembrane channel like 1
NCBI Official Symbol:
TMC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 88kDa
Purification:
Affinity purification
Research Area:
Neuroscience
Swissprot #:
Q8TDI8
User NOte:
Optimal dilutions for each application to be determined by the researcher.