MARVELD2 Antibody

ProSci
Product Code: PSI-23-758
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-758-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 5
Western blot analysis of extracts of SH-SY5Y cells, using MARVELD2 antibody (23-758) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
2 / 5
3 / 5
Immunohistochemistry of paraffin-embedded rat kidney using MARVELD2 antibody (23-758) (40x lens).
4 / 5
Immunohistochemistry of paraffin-embedded human liver damage using MARVELD2 antibody (23-758) (40x lens).
5 / 5
Immunohistochemistry of paraffin-embedded human stomach using MARVELD2 antibody (23-758) (40x lens).

Western blot analysis of extracts of SH-SY5Y cells, using MARVELD2 antibody (23-758) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 90s.
Immunohistochemistry of paraffin-embedded rat kidney using MARVELD2 antibody (23-758) (40x lens).
Immunohistochemistry of paraffin-embedded human liver damage using MARVELD2 antibody (23-758) (40x lens).
Immunohistochemistry of paraffin-embedded human stomach using MARVELD2 antibody (23-758) (40x lens).

Further Information

Additional Names:
MARVEL domain-containing protein 2, Tricellulin, MARVELD2, TRIC
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:200
Background:
The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MARVELD2 (NP_001033692.2).
NCBI Gene ID #:
153562
NCBI Official Name:
MARVEL domain-containing protein 2
NCBI Official Symbol:
MARVELD2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 64kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Signal Transduction
Swissprot #:
Q8N4S9
User NOte:
Optimal dilutions for each application to be determined by the researcher.