PFKFB2 Antibody
| Code | Size | Price |
|---|
| PSI-23-840-50uL | 50uL | £433.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Documents
Further Information
Additional Names:
PFKFB2, fructose-2, 6-bisphosphatase, cardiac isozyme, PFKFB, cardiac, OTTHUMP00000034286, OTTHUMP00000034285, 6PF-2-K/Fru-2, 6-P2ASE heart-type isozyme, 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2, PFK-2/FBPase-2, MGC138310, MGC138308, DKFZp781D2217, 6-biphosphatase 2, PFKFB2
Application Note:
WB: 1:500 - 1:2000
Background:
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 446-505 of human PFKFB2 (NP_006203.2).
NCBI Gene ID #:
5208
NCBI Official Name:
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
NCBI Official Symbol:
PFKFB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 54kDa
Purification:
Affinity purification
Research Area:
Signal Transduction
Swissprot #:
O60825
User NOte:
Optimal dilutions for each application to be determined by the researcher.