MYO5A Antibody

Contact us
ProSci
Product Code: PSI-23-929
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-23-929-50uL50uL£433.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Shipping:
Blue Ice or RT
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 5
Western blot analysis of extracts of various cell lines, using MYO5A antibody (23-929) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 10s.
2 / 5
3 / 5
Immunohistochemistry of paraffin-embedded human liver cancer using MYO5A antibody (23-929) at dilution of 1:100 (40x lens).
4 / 5
Immunohistochemistry of paraffin-embedded human prostate cancer using MYO5A antibody (23-929) at dilution of 1:100 (40x lens).
5 / 5
Immunohistochemistry of paraffin-embedded human rectum using MYO5A antibody (23-929) at dilution of 1:100 (40x lens).
❮❯

Western blot analysis of extracts of various cell lines, using MYO5A antibody (23-929) at 1:1000 dilution.<br/>Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.<br/>Lysates/proteins: 25ug per lane.<br/>Blocking buffer: 3% nonfat dry milk in TBST.<br/>Detection: ECL Basic Kit.<br/>Exposure time: 10s.
Immunohistochemistry of paraffin-embedded human liver cancer using MYO5A antibody (23-929) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human prostate cancer using MYO5A antibody (23-929) at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human rectum using MYO5A antibody (23-929) at dilution of 1:100 (40x lens).

Documents

Further Information

Additional Names:
MYO5A, MYR12, myoxin, myosin, heavy polypeptide kinase, myosin VA (heavy chain 12, myoxin), myosin VA, myosin V, MYO5, MYH12, GS1, dilute
Application Note:
WB: 1:500 - 1:2000

IHC: 1:50 - 1:100

IF: 1:50 - 1:100
Background:
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 950-1150 of human MYO5A (NP_000250.3).
NCBI Gene ID #:
4644
NCBI Official Name:
myosin VA (heavy chain 12, myoxin)
NCBI Official Symbol:
MYO5A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Observed: 240kDa
Purification:
Affinity purification
Research Area:
Cell Cycle, Neuroscience, Signal Transduction
Swissprot #:
Q9Y4I1
User NOte:
Optimal dilutions for each application to be determined by the researcher.