anti-CD38 (human), mAb (AT1) (APC)
| Code | Size | Price |
|---|
| ANC-187-060-120tests | 120 tests | £473.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Mouse IgG1kappa
Antibody Clonality: Monoclonal
Antibody Clone: AT1
Regulatory Status: RUO
Target Species: Human
Application: Fluorescence-activated cell sorting (FACS)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
ADP-ribosyl Cyclase 1; Cyclic ADP-ribose Hydrolase 1; T10
EClass:
32160000
Form (Short):
liquid
Formulation:
50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative).
Handling Advice:
Do not freeze.Protect from light.
Immunogen:
Human T cell tumor cells: CEM.
Labels - Conjugates:
APC
Long Description:
Monoclonal Antibody. Recognizes human CD38. Crossreactive with cynlomolgus macaque CD38, and recognizes a reduction-sensitive epitope. Isotype: Mouse IgG1kappa. Clone: AT1. Applications: FACS. Liquid. 50mM Sodium Phosphate pH 7.5, 500mM Potassium Chloride, 150mM NaCl, 15% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). Human CD38 is a type II transmembrane glycoprotein with bifunctional ectoenzyme activity catalyzing both synthesis and hydrolysis of cyclic ADP ribose. CD38 is involved in lymphocyte activation and adhesion to endothelium and has been identified as a counter-receptor of CD31.
Package Type:
Plastic Vial
Product Description:
Human CD38 is a type II transmembrane glycoprotein with bifunctional ectoenzyme activity catalyzing both synthesis and hydrolysis of cyclic ADP ribose. CD38 is involved in lymphocyte activation and adhesion to endothelium and has been identified as a counter-receptor of CD31.
Source / Host:
Purified from concentrated hybridoma tissue culture supernatant.
Specificity:
Recognizes human CD38. Crossreactive with cynlomolgus macaque CD38, and recognizes a reduction-sensitive epitope.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibody Conjugates
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at +4°C.
References
Anti-CD38 autoantibodies: Characterisation in new-onset Type I diabetes and latent autoimmune diabetes of the adult (LADA) and comparison with other islet autoantibodies: R. Mallone, et al.; Diabetologia 45, 1667 (2002) | Characterization and phylogenetic epitope mapping of CD38 ADPR cyclase in the cynomolgus macaque: E. Ferrero, et al.; BMC Immunol. 5, 21 (2004) | Targeting Multiple Myeloma with AMG 424, a Novel Anti-CD38/CD3 Bispecific T-cell?recruiting Antibody Optimized for Cytotoxicity and Cytokine Release: C.L. Zuch de Zafra, et al.; Clin. Cancer Res. 25, 3921 (2019)