IgM (human) Matched Antibody Pair

RevMab Biosciences
Product Code: REV-31-1023-MK
Product Group: Antibody Pairs
CodeSizePrice
REV-31-1023-MK-KI011 Set£617.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Clonality: Recombinant Antibody
Regulatory Status: RUO
Target Species: Human
Shipping:
Blue Ice
Storage:
+4°C

Images

1 / 1
Sandwich ELISA using RM121 as the capture antibody (100ng/well), and Biotinylated anti-human light chains (k+l) antibody RM129 (0.2ug/mL) as the detection antibody, followed by an alkaline phosphatase conjugated streptavidin.

Sandwich ELISA using RM121 as the capture antibody (100ng/well), and Biotinylated anti-human light chains (k+l) antibody RM129 (0.2ug/mL) as the detection antibody, followed by an alkaline phosphatase conjugated streptavidin.

Further Information

Alternate Names/Synonyms:
Immunoglobulin M
Assay Type:
Sandwich
EClass:
32160000
Handling Advice:
Avoid freeze/thaw cycles.
Kit Contains:
1) Capture Antibody: Anti-Human IgM Rabbit Monoclonal antibody, clone RM121, 100 ug at 1.0 mg/mL in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
2) Detection Antibody: Biotin Anti-Human Ig Light Chain Rabbit Monoclonal Antibody, Clone RM129, 25 ug at 1.0 mg/mL in 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide3) 10X Sample Diluent: Added to the tested sample to reduce non-specific background and noise
Long Description:
The Human IgM Matched Antibody Pairs is specific to Human IgM and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.
Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. In the case of humans and other mammals that have been studied, the spleen, where plasmablasts responsible for antibody production reside, is the major site of specific IgM production.
NCBI, Uniprot Number:
P01871
Package Type:
Vial
Product Description:
The Human IgM Matched Antibody Pairs is specific to Human IgM and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or goat immunoglobulin. The kit can be used for the detection of therapeutic antibodies from samples obtained from experimental animals to provide accurate pharmacokinetic (PK) data.Immunoglobulin M (IgM) is one of several isotypes of antibody (also known as immunoglobulin) that are produced by vertebrates. IgM is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. In the case of humans and other mammals that have been studied, the spleen, where plasmablasts responsible for antibody production reside, is the major site of specific IgM production.
Sample Type:
Serum
Specificity:
The antibody pair detects only human IgM. It does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG. There is no cross reactivity to any other immunoglobulins or IgG subclasses.
Transportation:
Non-hazardous
UNSPSC Category:
ELISA Kits
UNSPSC Number:
41116126
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.