anti-Neurofilament-L (human) Rabbit Monoclonal (RM280)

RevMab Biosciences
Product Code: REV-31-1163-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1163-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM280
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C

Images

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Immunohistochemical staining of formalin fixed and paraffin embedded human brain tissue sections using Anti-Neurofilament-L (NF-L) Rabbit Monoclonal Antibody (Clone RM280) at a 1:2500 dilution.

Immunohistochemical staining of formalin fixed and paraffin embedded human brain tissue sections using Anti-Neurofilament-L (NF-L) Rabbit Monoclonal Antibody (Clone RM280) at a 1:2500 dilution.

Further Information

Alternate Names/Synonyms:
NF-L
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of human Neurofilament-L (NF-L).
Long Description:
Recombinant Antibody. This antibody reacts to human Neurofilament-L (NF-L). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate or 10nm diameter filaments found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-L is the light or low molecular weight microfilament subunit (~70 kDa), NF-M the medium weight microfilament subunit (~160kDa) and NF-H is the heavy or high molecular weight microfilament subunit (~180-220 kDa), with some variation in different species. Antibodies againts the various neurofilament subunits are very useful cell type markers since the proteins are quite abundant and biochemically stable.
NCBI, Uniprot Number:
P07196
Package Type:
Vial
Product Description:
Involved in the maintenance of neuronal caliber, neurofilaments are the intermediate or 10nm diameter filaments found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. NF-L is the light or low molecular weight microfilament subunit (~70 kDa), NF-M the medium weight microfilament subunit (~160kDa) and NF-H is the heavy or high molecular weight microfilament subunit (~180-220 kDa), with some variation in different species. Antibodies againts the various neurofilament subunits are very useful cell type markers since the proteins are quite abundant and biochemically stable.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human Neurofilament-L (NF-L).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.