anti-p120-catenin (human) Rabbit Monoclonal (RM353)
| Code | Size | Price |
|---|
| REV-31-1239-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM353
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Catenin delta-1; Cadherin-associated Src Substrate
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of human p120 catenin (Catenin delta-1).
Long Description:
Recombinant Antibody. This antibody reacts human p120 catenin (Catenin delta-1). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Catenins are proteins associated with complexes that contain cadherin cell adhesion molecules. p120-Catenin (delta-1-catenin) is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development. It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state. Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins. These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor. p120-Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
NCBI, Uniprot Number:
O60716
Package Type:
Vial
Product Description:
Catenins are proteins associated with complexes that contain cadherin cell adhesion molecules. p120-Catenin (delta-1-catenin) is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development. It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state. Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins. These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor. p120-Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts human p120 catenin (Catenin delta-1).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.