anti-ACTA2 Rabbit Monoclonal (RM253)
| Code | Size | Price |
|---|
| REV-31-1133-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM253
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Actin, Aortic Smooth Muscle; alpha Smooth Muscle Actin; Alpha-actin-2; Cell Growth-inhibiting Gene 46 Protein
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A synthetic peptide corresponding to the N-terminus of human alpha smooth muscle Actin.
Long Description:
Recombinant Antibody. This antibody reacts to human and mouse alpha smooth muscle Actin (alpha-Actin-2). This antibody may also react to bovine or rat alpha smooth muscle Actin, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Actins are a family of globular multi-functional proteins that form microfilaments and are important for cell movement and the tensing (contraction) of muscles. ACTA2 (alpha smooth muscle actin; α-SMA) is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. Smooth muscles line the internal organs, including the blood vessels, stomach, and intestines. Within smooth muscle cells, smooth muscle α-2 actin forms the core of structures called sarcomeres, which are necessary for muscles to contract. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, Moyamoya disease and multisystemic smooth muscle dysfunction syndrome. ACTA2 is often used as a marker of myofibroblast formation.
NCBI, Uniprot Number:
P62736
Package Type:
Vial
Product Description:
Actins are a family of globular multi-functional proteins that form microfilaments and are important for cell movement and the tensing (contraction) of muscles. ACTA2 (alpha smooth muscle actin; alpha-SMA) is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. Smooth muscles line the internal organs, including the blood vessels, stomach, and intestines. Within smooth muscle cells, smooth muscle alpha-2 actin forms the core of structures called sarcomeres, which are necessary for muscles to contract. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, Moyamoya disease and multisystemic smooth muscle dysfunction syndrome. ACTA2 is often used as a marker of myofibroblast formation.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human and mouse alpha smooth muscle Actin (alpha-Actin-2). This antibody may also react to bovine or rat alpha smooth muscle Actin, as predicted by immunogen homology.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.