anti-Spastin (human) Rabbit Monoclonal (RM346)

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RevMab Biosciences
Product Code: REV-31-1232-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1232-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM346
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C

Images

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Immunohistochemical staining of formalin fixed and paraffin embedded human Tonsil tissue section using anti-Spastin rabbit monoclonal antibody (Clone RM346) at a 1:1000 dilution.
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Immunohistochemical staining of formalin fixed and paraffin embedded human Tonsil tissue section using anti-Spastin rabbit monoclonal antibody (Clone RM346) at a 1:1000 dilution.

Documents

Further Information

Alternate Names/Synonyms:
Spastic Paraplegia 4 Protein
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the N-terminus of human Spastin.
Long Description:
Recombinant Antibody. This antibody reacts to human Spastin. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Spastin is a microtubule-severing protein that cleaves longer microtubules (MTs) to shorter ones. The severing of MT regulates its numbers and mobility, and the distribution of the plus-end. This has also been related to membrane trafficking of microtubules. Mutations in the spastin gene SPG4 is the main cause for hereditary spastic paraplegia, a neurodegenerative disorder mainly occurring in corticospinal tracks.
NCBI, Uniprot Number:
Q9UBP0
Package Type:
Vial
Product Description:
Spastin is a microtubule-severing protein that cleaves longer microtubules (MTs) to shorter ones. The severing of MT regulates its numbers and mobility, and the distribution of the plus-end. This has also been related to membrane trafficking of microtubules. Mutations in the spastin gene SPG4 is the main cause for hereditary spastic paraplegia, a neurodegenerative disorder mainly occurring in corticospinal tracks.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human Spastin.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.