anti-Arginase-1 (human) Rabbit Monoclonal (RM377)
| Code | Size | Price |
|---|
| REV-31-1263-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM377
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
ARG1
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of human Arginase-1 (ARG1).
Long Description:
Recombinant Antibody. This antibody reacts to human Arginase-1 (ARG1). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Arginase I, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes which plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia, a buildup of arginine and ammonia in the blood. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general. Anti-Arginase I is highly specific for hepatocytes and is therefore a sensitive and specific marker of benign and malignant hepatic tumors.
NCBI, Uniprot Number:
P05089
Package Type:
Vial
Product Description:
Arginase I, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes which plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia, a buildup of arginine and ammonia in the blood. Arginase is involved in the nitric oxide (NO) pathway and immune cell arginine metabolism. It is fundamentally involved in cancer, inflammation, infections, fibrotic diseases, neurobiology, pregnancy and immune regulation in general. Anti-Arginase I is highly specific for hepatocytes and is therefore a sensitive and specific marker of benign and malignant hepatic tumors.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human Arginase-1 (ARG1).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.