anti-Calretinin (human) Rabbit Monoclonal (RM324)
| Code | Size | Price |
|---|
| REV-31-1211-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM324
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
CALB2
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to N-terminus of human Calretinin.
Long Description:
Recombinant Antibody. This antibody reacts to human Calretinin. It may also react to mouse or rat Calretinin, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Calretinin, also known as calbindin 2 (formerly 29 kDa calbindin), is a calcium-binding protein involved in calcium signaling. It is a troponin C superfamily protein having six EF-hand structural motifs. The EF motif allows the protein to bind calcium, and function in calcium signaling, calcium buffering, modulating neuronal excitability and message targeting. Calretinin is abundantly expressed in neurons including retina and cortical interneurons. Expression was found in different neurons than of the similar vitamin D-dependent calcium-binding protein, calbindin-28kDa. Loss of expression of calretinin in hippocampal interneurons has been suggested to be relevant in temporal lobe epilepsy. Calretinin is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.
NCBI, Uniprot Number:
P22676
Package Type:
Vial
Product Description:
Calretinin, also known as calbindin 2 (formerly 29 kDa calbindin), is a calcium-binding protein involved in calcium signaling. It is a troponin C superfamily protein having six EF-hand structural motifs. The EF motif allows the protein to bind calcium, and function in calcium signaling, calcium buffering, modulating neuronal excitability and message targeting. Calretinin is abundantly expressed in neurons including retina and cortical interneurons. Expression was found in different neurons than of the similar vitamin D-dependent calcium-binding protein, calbindin-28kDa. Loss of expression of calretinin in hippocampal interneurons has been suggested to be relevant in temporal lobe epilepsy. Calretinin is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human Calretinin. It may also react to mouse or rat Calretinin, as predicted by immunogen homology.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.