anti-Syntaxin-1A (human) Rabbit Monoclonal (RM367)
| Code | Size | Price |
|---|
| REV-31-1253-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM367
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
Neuron-specific Antigen HPC-1
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to residues near N-terminus of human Syntaxin-1A.
Long Description:
Recombinant Antibody. This antibody reacts to human, mouse, and rat Syntaxin-1A. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxin-1A (Neuron-specific antigen HPC-1) belongs to the Q-SNARE protein family that participates in exocytosis. Syntaxin-1A is a t-SNARE abundantly expressed in most neurons and localized on the neuronal plasma membrane, where it participates in the formation of the trans-SNARE complex by engaging t-SNARE SNAP25 (synaptosomal-associated protein 25) and v-SNARE synaptobrevin (a.k.a. vesicle-associated membrane protein2 or VAMP2) to allow fusion between the synaptic vesicle and plasma membrane. Two types of syntaxin 1 isoforms exist. Syntaxin-1A is a key protein in ion channel regulation and synaptic exocytosis.
NCBI, Uniprot Number:
Q16623
Package Type:
Vial
Product Description:
Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxin-1A (Neuron-specific antigen HPC-1) belongs to the Q-SNARE protein family that participates in exocytosis. Syntaxin-1A is a t-SNARE abundantly expressed in most neurons and localized on the neuronal plasma membrane, where it participates in the formation of the trans-SNARE complex by engaging t-SNARE SNAP25 (synaptosomal-associated protein 25) and v-SNARE synaptobrevin (a.k.a. vesicle-associated membrane protein2 or VAMP2) to allow fusion between the synaptic vesicle and plasma membrane. Two types of syntaxin 1 isoforms exist. Syntaxin-1A is a key protein in ion channel regulation and synaptic exocytosis.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human, mouse, and rat Syntaxin-1A.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.