anti-CPS1 (human) Rabbit Monoclonal (RM395)

RevMab Biosciences
Product Code: REV-31-1281-00
Product Group: Primary Antibodies
CodeSizePrice
REV-31-1281-00-R100100 ul£455.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM395
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C

Images

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Immunohistochemical staining of formalin fixed and paraffin embedded human liver tissue section using anti-CPS1 rabbit monoclonal antibody (Clone RM395) at a 1:100 dilution.

Immunohistochemical staining of formalin fixed and paraffin embedded human liver tissue section using anti-CPS1 rabbit monoclonal antibody (Clone RM395) at a 1:100 dilution.

Further Information

Alternate Names/Synonyms:
Carbamoyl-phosphate Synthase 1; CPSase1
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to Human CPS1.
Long Description:
Recombinant Antibody. This antibody reacts to human CPS1. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Carbamoyl phosphate synthetase I (CPS1 or CPSI) is a ligase enzyme located in the mitochondria involved in the production of urea. It transfers an ammonia molecule from glutamine or glutamate to a molecule of bicarbonate that has been phosphorylated by a molecule of ATP. The resulting carbamate is then phosphorylated with another molecule of ATP. The resulting molecule of carbamoyl phosphate leaves the enzyme. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. Mutations in this gene have been associated with carbamoyl phosphate synthetase 1 deficiency (CPS1D), susceptibility to persistent pulmonary hypertension and susceptibility to venoocclusive disease after bone marrow transplantation.
NCBI, Uniprot Number:
P31327
Package Type:
Vial
Product Description:
Carbamoyl phosphate synthetase I (CPS1 or CPSI) is a ligase enzyme located in the mitochondria involved in the production of urea. It transfers an ammonia molecule from glutamine or glutamate to a molecule of bicarbonate that has been phosphorylated by a molecule of ATP. The resulting carbamate is then phosphorylated with another molecule of ATP. The resulting molecule of carbamoyl phosphate leaves the enzyme. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. Mutations in this gene have been associated with carbamoyl phosphate synthetase 1 deficiency (CPS1D), susceptibility to persistent pulmonary hypertension and susceptibility to venoocclusive disease after bone marrow transplantation.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human CPS1.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.