anti-Desmin Rabbit Monoclonal (RM234)
| Code | Size | Price |
|---|
| REV-31-1124-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM234
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
DESM
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to human Desmin.
Long Description:
Recombinant Antibody. This antibody reacts to human and mouse Desmin. This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue. Desmin (DES) mutations have been associated with restrictive, dilated, idiopathic, arrhythmogenic and non-compaction cardimyopathy.
NCBI, Uniprot Number:
P17661
Package Type:
Vial
Product Description:
Desmin (approximately 53 kDa) exhibits a high degree of tissue specificity, its expression being predominantly confined to all types of muscle cells (cardiac, skeletal and smooth muscle). Regulation of desmin expression is stage and tissue-specific, since it is induced during terminal development of, for example, skeletal muscle cell differentiation. In skeletal en cardiac muscle cells desmin is localized in the Z-disk region and at the intercalated disk. The expression pattern of desmin in smooth muscle is much more heterogenous. Coexpression of vimentin and desmin has been observed in tumors derived from muscle tissue. Desmin (DES) mutations have been associated with restrictive, dilated, idiopathic, arrhythmogenic and non-compaction cardimyopathy.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human and mouse Desmin. This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.