anti-CD5 (human) Rabbit Monoclonal (RM314)
| Code | Size | Price |
|---|
| REV-31-1200-00-R100 | 100 ul | £455.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: RM314
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
T-cell Surface Glycoprotein CD5
Concentration:
N/A
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
A peptide corresponding to the C-terminus of human CD5.
Long Description:
Recombinant Antibody. This antibody reacts to human CD5. Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein, also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), peripheral blood dendritic cells and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 modulates T and B cell receptor signaling, thymocyte maturation and T-B cell interactions upon binding to ligands such as CD72. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
NCBI, Uniprot Number:
P06127
Package Type:
Vial
Product Description:
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein, also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), peripheral blood dendritic cells and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 modulates T and B cell receptor signaling, thymocyte maturation and T-B cell interactions upon binding to ligands such as CD72. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.
Purity:
Protein A purified.
Source / Host:
Rabbit
Specificity:
This antibody reacts to human CD5.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.