anti-IgG Fc (mouse) Goat Monoclonal (RMG06)

Immunoglobulin G

1 mg/ml

32160000

liquid

Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.

Avoid freeze/thaw cycles.

Mouse IgG.

Recombinant Antibody. This antibody reacts to the Fc region of Mouse IgG, including IgG1, IgG2a, and IgG2b. It shows very slight reaction with mouse IgG3. No cross reactivity with IgM, IgA, IgE, human IgG, rat IgG, or rabbit IgG. Applications: IP, ICC, IHC, FACS, ELISA. Source: Goat. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Immunoglobulin G (IgG), a monomer, is the predominant Ig class present in serum. Produced as part of the secondary immune response to an antigen, this class of immunoglobulin constitutes approximately 75% of total serum Ig. In mice there are four different IgG subclasses known, namely IgG1, IgG2a/c, IgG2b, and IgG3, which are determined by their respective C regions γ1, γ2a/c, γ2b, and γ3. The mutually exclusive occurrence of either IgG2a or IgG2c is determined by the genetic background of the mouse strain; however, both IgG2a and IgG2c are thought to have similar characteristics. Because of its relative abundance and excellent specificity toward antigens, IgG is the principle antibody used in immunological research and clinical diagnostics. This anti-mouse secondary antibody has well-characterized specificity for mouse IgG immunoglobulins Fc region and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody.

N/A

Vial

Immunoglobulin G (IgG), a monomer, is the predominant Ig class present in serum. Produced as part of the secondary immune response to an antigen, this class of immunoglobulin constitutes approximately 75% of total serum Ig. In mice there are four different IgG subclasses known, namely IgG1, IgG2a/c, IgG2b, and IgG3, which are determined by their respective C regions gamma1, gamma2a/c, gamma2b, and gamma3. The mutually exclusive occurrence of either IgG2a or IgG2c is determined by the genetic background of the mouse strain; however, both IgG2a and IgG2c are thought to have similar characteristics. Because of its relative abundance and excellent specificity toward antigens, IgG is the principle antibody used in immunological research and clinical diagnostics. This anti-mouse secondary antibody has well-characterized specificity for mouse IgG immunoglobulins Fc region and is useful in the detection, sorting or purification of its specified target. In general, secondary antibodies offer increased versatility enabling users to use many detection systems (e.g. HRP, AP, fluorescence). They can also provide greater sensitivity through signal amplification as multiple secondary antibodies can bind to a single primary antibody.

Protein G purified.

Goat

This antibody reacts to the Fc region of Mouse IgG, including IgG1, IgG2a, and IgG2b. It shows very slight reaction with mouse IgG3. No cross reactivity with IgM, IgA, IgE, human IgG, rat IgG, or rabbit IgG.

Non-hazardous

Secondary Antibodies

12352203

Stable for at least 1 year after receipt when stored at -20°C.