SARS-CoV-2 (COVID-19) Nucleocapsid Antibody [6G9]

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ProSci
Product Code: PSI-93-300
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-93-300-0.1mg0.1mg£886.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Antibody Isotype: Human IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 6G9
Regulatory Status: RUO
Target Species: Virus
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
blue ice or RT
Storage:
24 months from manufacturing at <-20 ˚C; 1 month, 2 to 8 ˚C under sterile conditions.

Images

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Immobilized 2019-nCoV Nucleocapsid Protein (Cat#92-728) at 5.0ug/ml (100uL/well) can bind 2019-nCoV NP Antibody (6G9) , the EC50 for this effect is 5-30ng/ml.
2 / 5
Loaded 2019-nCoV Nucleocapsid Protein-His (Cat#92-728) on HIS1K Biosensor, can bind 2019-nCoV NP Antibody (6G9)(Cat#93-300) with an affinity constant of 1.15 nM as determined in BLI assay.
3 / 5
4 / 5
Freeze-thaw stability is tested by repeated freeze-thaw cycles. The result showed that product bioactivity is no signi?cant di?erences after freeze-thawing 10 times.
5 / 5
Stability is con?rmed by binding ability with 2019-nCoV Nucleocapsid Protein (Cat#92-728). The result showed that product bioactivity is no significant differences among these samples.
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Immobilized 2019-nCoV Nucleocapsid Protein (Cat#92-728) at 5.0ug/ml (100uL/well) can bind 2019-nCoV NP Antibody (6G9) , the EC50 for this effect is 5-30ng/ml.
Loaded 2019-nCoV Nucleocapsid Protein-His (Cat#92-728) on HIS1K Biosensor, can bind 2019-nCoV NP Antibody (6G9)(Cat#93-300) with an affinity constant of 1.15 nM as determined in BLI assay.
Freeze-thaw stability is tested by repeated freeze-thaw cycles. The result showed that product bioactivity is no signi?cant di?erences after freeze-thawing 10 times.
Stability is con?rmed by binding ability with 2019-nCoV Nucleocapsid Protein (Cat#92-728). The result showed that product bioactivity is no significant differences among these samples.

Documents

Further Information

Additional Names:
SARS-CoV-2 (COVID-19) Nucleocapsid Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Nucleocapsid protein, N protein, Nucleocapsid Phosphoprotein
Application Note:
Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.
Background:
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Buffer:
PBS, pH 7.4
Concentration:
5.0 mg/ml (+/- 10 %)
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
full length recombinant Nucleocapsid Protein
NCBI Gene ID #:
43740575
NCBI Official Name:
nucleocapsid phosphoprotein
NCBI Official Symbol:
N
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Protein Accession #:
QHD43423
Protein GI Number:
1820552696
Purification:
?95 %
Research Area:
Infectious Disease,COVID-19
SPECIFICITY:
Antibody recognizes 2019-nCoV Nucleocapsid Protein
Swissprot #:
P0DTC9
User NOte:
Optimal dilutions for each application to be determined by the researcher.